CALDERA

Pharmaceuticals  

Caldera Pharmaceuticals, Inc.
278-D DP Road, Los Alamos, NM 87544
175 W. Jackson #2230, Chicago, IL 60604

ph: 505-661-2420
fax: 302-347-1326

info@cpsci.com

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Technology

XRpro® non-destructively quantifies the elemental composition of molecules. Samples are excited with x-rays, making their atoms fluoresce with characteristic x-ray signals. XRpro® quantifies these x-ray signals to assess drug and protein behavior, including binding, activity, and post-translational modifications. All of this occurs in one second.

XRpro® improves drug development with low cost, high-throughput, completely label-free measurements:

  • XRpro® provides both safety and efficacy measurements for compounds in single one second measurements.
  • XRpro® is automated to characterize 1,000,000 compounds per month.
  • XRpro® saves the typical user $500,000 per month by eliminating labels.
  • XRpro® measures multiple on-target and off-target reactions simultaneously, collecting data efficiently and inexpensively.
  • XRpro® measures binding and function of critical targets and cofactors.
  • XRpro® quantifies post-translational modifications and cofactors, such as phosphorylation, sulfonation, ATP, and metals.

 Applications:

  • target binding

  • target inhibition

  • compound stability

  • off-target binding

  • off-target inhibition

  • cofactor binding  




Copyright 2012 Caldera Pharmaceuticals, Inc.

All rights reserved.

Caldera Pharmaceuticals, Inc.
278-D DP Road, Los Alamos, NM 87544
175 W. Jackson #2230, Chicago, IL 60604

ph: 505-661-2420
fax: 302-347-1326

info@cpsci.com